WHAT IS POMELLA?
Understanding what Pomella is helps explain what sets it apart from the rest!
In a market flooded with numerous pomegranate products and antioxidant offerings, it can be difficult to decipher what sets each apart from the crowd and how that can apply to the finished product you are formulating.
We're here to clear up the confusion!
Punicalagins are a group of potent antioxidants unique to the pomegranate fruit, which Pomella® is standardized to. These ellagitannin polyphenols are water-soluble, highly bioavailable, supported by safety data, and they are shown to possess a high absorption rate. Not only are punicalagins known to offer a powerful kick of antioxidant properties on their own, they are among the most ferocious scavengers of free radicals, or unstable molecules that can cause damage to the body over time. They display some other interesting activities as well, such as potent modulation of inflammatory biomarkers and protective effects of DNA and cellular signaling. Punicalagins are unique because they are able to break apart, or hydrolyze, into smaller polyphenols (such as ellagic acid) once in the blood stream, and extensively metabolize and absorb into target tissues. However, there is a catch to pomegranate bioavailability. Researchers found that if punicalagins hydrolyze before they enter the bloodstream, the molecules do not absorb; they need to be attached to the primary polyphenol to be bioavailable.
Pomella’s patented extraction process delivers an ellagitannin rich profile standardized to punicalagin content. Indeed, these ellagitannins found in the pomegranate are capable of reducing oxidative stress. Oxidative stress can be defined as an imbalance in free radicals, or reactive oxygen species (ROS), and antioxidant defenses. Thus the importance of antioxidants, such as Pomella. For example, in healthy human volunteers, a single dose of Pomella® led to a significant 32% increase of antioxidant activity in the blood. Bioactive punicalagin derived metabolites were detected in half an hour after dosing [1]. In fact, metabolites of punicalagins have been detected in the body throughout a timeframe of 48-hours after consumption [2].
Pomella's antioxidant offerings go beyond the basics for a well-being ingredient solution that tackles a variety of health applications.
For more information and the latest research on Pomella, visit the SCIENCE page - or watch the video again below!
References:
1- Mertens-Talcott SU et al. J Agric Food Chem. 2006 Sep 06. 54(23): 8956-8961. EPub 2006 Oct 13.
2- Seeram NP et al. J Med Food. 2008 Jan 23. 11(2): 390-394. DOI: 10.1089/jmf.2007.650
